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郑林

发布日期:2020-01-08    作者:     来源:     点击:

       郑林,博士,少数民族基因与疾病及民族药开发研究方向学术带头人,教授,博导,贵州省药学会药学青年专业委员会副主任委员、中华中医药学会中医药现代化联盟理事。近年来主持各级科研项目16项,其中国家自然科学基金4项、国家重点研发计划子课题1项、省级科研项目8项;以第一完成人获贵州省科技进步奖一等奖和贵州医学科技奖一等奖,作为参与人获贵州省科技成果奖7项。以第一或通讯作者发表论文50余篇。获得发明专利授权10项。

研究方向

中药、民族药药效物质基础与质量控制研究及新药研究开发

代表性论文

1. Li Yuan, Hao Chen, Xue Ma, Jie Pan, Zi-Peng Gong, Si-Ying Chen, Yue-Ting Li, Ai-Min Wang, Lin Zheng*, Yong Huang*. Herb-Drug Interaction: Application of a UPLC-MS/MS Method to Determine the Effect of Polygonum capitatum Extract on the Tissue Distribution and Excretion of Levofloxacin in Rats. Evid Based Complement Alternat Med. 2020;2020:2178656.

2. Hao Chen#, Li Yuan#, Xue Ma, Zi-Peng Gong, Yue-Ting Li, Si-Ying Chen, Jie Pan, Ai-Min Wang, Lin Zheng*, Yong Huang*. Herb-drug interaction: the effect of Polygonum capitatumextract on pharmacokinetics of levofloxacin in rats. J Pharm Biomed Anal. 2021 Feb 20;195:113832.

3. Lin Zheng#, Yueting Li#, Zuying Zhou , Wenying Xiang , Zipeng Gong, Siying Chen, Yonglin Wang, Aimin Wang, Yanyu Lan, Yongjun Li*,Yong Huang*. Comparative pharmacokinetics of quercitrin, astragalin, afzelin, and taxifolin in plasma after oral administration of Polygonum orientaleinflorescence in sham-operated and myocardial ischemia-reperfusion injury rats. Xenobiotica. 2020;50(7):822-830.

4. Chang Yang, Tao Xia, Changquan Wang, Huiyuan Sun, Yongjun Li, Zipeng Gong, Yueting Li, Lin Zheng*, Yong Huang*. Using the UPLC-ESI-Q-TOF-MSE method and intestinal bacteria for metabolite identification in the nonpolysaccharide fraction from Bletilla striata. Biomed Chromatogr. 2019;33(11):e4637.

5. Lin Zheng#, Yueting Li#, Zuying Zhou , Wenying Xiang , Zipeng Gong, Siying Chen, Yonglin Wang, Aimin Wang, Yanyu Lan, Yongjun Li*,Yong Huang*. Comparative pharmacokinetics of quercitrin, astragalin, afzelin, and taxifolin in plasma after oral administration of Polygonum orientaleinflorescence in sham-operated and myocardial ischemia-reperfusion injury rats. Xenobiotica. 2020;50(7):822-830.