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何燕

发布日期:2020-01-08    作者:     来源:     点击:

何燕,硕士、教授、博士生导师。中国生化学与分子生物学会会员,《中华地方病学杂志》第八、第九届编辑委员会委员,贵州医科大学优秀教师(2024,2019)、骨干教师(2018~2021);农工党贵州省第七、第八届委员会委员。近五年主持国家自然科学基金3项、贵州省科技支撑计划项目2项、贵阳市科技计划项目和贵州省卫健委科技基金项目各1项,作为骨干参与国家科技支撑计划项目、国家自然科学基金、贵州省各类科研项目等多项课题研究。先后获贵州省研究生教学成果特等奖1项(第五获奖人)、贵州省科技进步三等奖1项(第三获奖人)、贵阳市科技进步二等奖1项(第二获奖人)、贵州省医学会科技一等奖1项(第二获奖人),国家发明专利授权1项(第三授权人),软件著作权登记1项。以第一或通讯作者身份在国内外期刊发表论文60余篇,其中SCI收录11篇;参编专著2部。培养硕士研究生18名,顺利毕业10名,获贵州省优秀硕士论文奖1项,贵州医科大学优秀硕士论文一等奖3项、二等奖1项。

研究方向:

少数民族常见疾病基因改变及遗传背景研究

代表性论文:

1.Luo Y#, Chi A#, Guo X#, Song J, Zhang X, Dong Y, Wang C, Zhang T, Deng J, Ma J, Li X, Shan K, Guan Z, He Y*. Genetic mixed diversity landscape in the paternal lineages of 11 populations inhabiting Southwest China according to the analysis of 25 Y-STRs[J].BMC Ecol Evol. 2025 Jun 9;25(1):61.

2.Song J#, Zhao A#, Li R, Luo Y, Dong Y, Wang C, Zhang T, Deng J, Qi X, Guan Z, He Y*. Association of PPARGC1A gene polymorphism and mtDNA methylation with coal-burning fluorosis: a case-control study[J]. BMC Genomics. 2024 Sep 30;25(1): 908.

3.He Y#, Lei C#, Wang C, Zeng S, Zhang T, Luo F, Li R, Li X, Zhao A, Xiao D, Luo Y, Shan K, Qi X*, Jin X*. A comprehensive whole genome database of ethnic minority populations[J]. Sci Rep. 2024 Jun 17;14(1):13954.

4.Li R#, Song J#, Zhao A, Diao X, Zhang T, Qi X, Guan Z, An Y, Ren L*, Wang C*,He Y*. Association of APP gene polymorphisms and promoter methylation with essential hypertension in Guizhou: a case-control study [J].Hum Genomics. 2023 Mar 20; 17(1): 25.

5.Li R#, Zhao A#, Diao X, Song J, Wang C, Li Y, Qi X, Guan Z, Zhang T*,He Y*. Polymorphism of NOS3 gene and its association with essential hypertension in Guizhou populations of China[J].PLoS One. 2023 Feb 9;18(2): e0278680.

6.He Y, Ren LY, Shan KR, Zhang T, Wang CJ, Guan ZZ*. Characterization of polymorphisms in the mitochondrial DNA of twelve ethnic groups in the Guizhou province of China.Mitochondrial DNA A DNA Mapp Seq Anal. 2016;27(1):365-70.

7.Zhang C#,He Y#, Shan KR, Tan K, Zhang T, Wang CJ, Guan ZZ*. Correlations between polymorphisms in the uridine diphosphate-glucuronosyltransferase 1A and C-C motif chemokine receptor 5 genes and infection with the hepatitis B virus in three ethnic groups in China.J Int Med Res. 2018 Feb;46(2):739-751.

8.He Y, Yuan C, Chen L, Lei M, Zellmer L, Huang H, Liao DJ*. Transcriptional-Readthrough RNAs Reflect the Phenomenon of "A Gene Contains Gene(s)" or "Gene(s) within a Gene" in the Human Genome, and Thus Are Not Chimeric RNAs.Genes (Basel). 2018 Jan 16;9(1):40.

9.He Y, Yuan C, Chen L, Liu Y, Zhou H, Xu N, Liao DJ*. While it is not deliberate, much of today's biomedical research contains logical and technical flaws, showing a need for corrective action.Int J Med Sci. 2018 Jan 19;15(4):309-322.

联系方式:

通信地址:贵州省贵安新区安康大道6号贵州医科大学分子生物学重点实验室(务本楼3-10室)(561113)

E-mail:annieheyan@gmc.edu.cn